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Confocal microscopy

Confocal microscopy equipment at SLCU comprises three point scanning confocals:

  • Zeiss LSM780 upright equipped with spectral detector and ablation laser. This microscope is particularly good for imaging problematic fluorophore combinations and for tile scanning.
  • Leica TCS SP8 upright equipped with sensitive HyD detectors and both standard and resonant scanners. This is particularly good for faster, low signal imaging.
  • Zeiss LSM700 upright. This microscope is particularly good for imaging the new generation of red fluorescent proteins e.g mCherry and mOrange.
  • Leica-Renishaw SP8-FLIMan. A new type of confocal enabling label-free organelle imaging and Raman detection of molecules. In summary this system enables SLCU to image, in living tissue, the ‘Chemistry of Cells’.

And a spinning disk microscope:

  • A feature packed inverted spinning disk setup centred around a Nikon Ti Eclipse assembled by Cairn Research. This microscope is particularly good for high sensitivity timelapse imaging.

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How to become a giant cell? Fluctuations in a key regulator guide cell size in flower organs.

Mar 06, 2017

A key regulator has been discovered to determine cell size in flowers through random fluctuations. Counterintuitively, this randomness can lead to patterns. This finding helps us to understand how biological patterns are initiated, how shape and size are determined during growth, and may lead to important discoveries improving crop yields.

Ottoline Leyser honoured with the 2017 FEBS | EMBO Women in Science Award

Jan 09, 2017

EMBO and FEBS announce SLCU Director Professor Ottoline Leyser as the recipient of the tenth FEBS | EMBO Women in Science Award.

Plant ‘thermometer’ discovered that triggers springtime budding by measuring night-time heat

Oct 27, 2016

A photoreceptor molecule in plant cells has been found to moonlight as a thermometer after dark – allowing plants to read seasonal temperature changes. Scientists say the discovery could help breed crops that are more resilient to the temperatures expected to result from climate change.

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