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Leica-Renishaw SP8-FLIMan

A partnership between SLCU and three companies; Leica Microsystems, Leica Industrial and Renishaw, the FLIMan allows a diverse range of specialist techniques in addition to high-end confocal microscopy:

- Real time imaging of protein-protein interactions and biosensors using FLIM.

- Label-free organelle imaging using Raman, in addition to fluorescently labelled reporters.

- Direct imaging of molecular constituents of cells and tissues with applications to phytohormones.


Leica SP8 confocal with dual channel FLIM, 2x HyD SMD detectors, 2x PMTs, 1x t-PMT, automatic stage for use in both confocal and Raman modes. Renishaw InVia Raman system with Rencam CCD and Andor EMCCD detectors. Conversion kit for liquid samples.


Leica LAS X with FLIM module, Picoquant software for photon counting. WiRE software for Raman spectral acquisition and


(Confocal) Pulsed 405nm, 440nm, 470nm. Continuous 440nm, 488nm, 514nm and 552nm
(Raman) 532nm, 785nm.


(SP8+Raman) 20x dry, 20x 0.75NA multi-immersion, 25x 0.95NA water dipping, 63x 1.2NA water, 63x 1.4NA oil.
(Raman only) 5x dry, 20x dry, 50x dry, 20x 0.75NA multi-immersion.

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Rare mineral discovered in plants for first time

Mar 05, 2018

A rare mineral that holds enticing potential as a new material for industrial and medical applications has been discovered on alpine plants through a collaboration between Sainsbury Laboratory and Cambridge University Botanic Garden.

Plants feel the heat

Feb 13, 2018

Sainsbury Laboratory scientists have solved a 79-year-old mystery by discovering how plants vary their response to heat stress depending on the time of day.

Fast-talking plants increase flower production within 24-hours of soil nutrient application

Jan 24, 2018

The molecular mechanisms enabling plants to quickly adapt their rate of flower production in response to changing nutrient levels in soil have been revealed by researchers at the Sainsbury Laboratory at the University of Cambridge.

Re-wiring cells by crossing kingdoms

Jan 22, 2018

Game-changing synthetic biology developments that could help address global health and agriculture challenges will be examined at a three-day international synthetic biology symposium at the Sainsbury Laboratory, University of Cambridge, this spring (16-18 April 2018).

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