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Sainsbury Laboratory


I had some experience of working with plant biochemistry during my undergraduate degree, when I had an internship position at the Research Institute of Regional Problems in Samarkand with a placement at the Research Institute of Chemistry of Plant Substances in Tashkent, as part of my project. This collaboration resulted in my Bachelor’s Diploma thesis, which focused on a specific biochemical adaptation mechanism of Artemisia diffusa to drought and high salinity stress environments. After graduation, I continued working at the Institute of Regional Problems under Dr. Kristina Toderich, where our group monitored the quality of soil and water in the Zerafshan river basin to investigate the impact these abiotic environmental factors had on the flora of the region.

For post-graduate research I decided to move away from plants and learn more about the development of nervous systems. I did my PhD degree under Dr. Matthias Landgraf, aiming to characterise a subset of interneurons involved in locomotion of Drosophila melanogaster larvae. During the course of my studies I gained understanding and experience in diverse genetic expression tools available in the fly to label, manipulate, characterise and catalogue individual neurons. I routinely used various micro-dissection techniques, optimised antibody staining protocols, as well as widefield and confocal fluorescent microscopy imaging systems. The nature of my project relied on combining genetic, immunohistochemistry and imaging methods to create a coherent approach aimed at resolving the 3D morphology of individual cells and their subcellular compartments in the context of anatomic landmark structures in the central nervous system.

This prepared me well for my current role of a lab manager with Dr. Sebastian Schornack, where I perform both administrative and research duties. My administrative role includes ensuring smooth day-to-day operation of the group: provision of resources, consumables and equipment; liaison with Facilities and Support Services; training postdocs and students as well as ensuring compliance with safety regulations; maintaining bacterial, oomycete and liverwort stocks, and generating stable transgenic N. benthamiana lines. My research role focuses on localisation of various sub-cellular markers to plant-microbe interfaces. To this end, I use microdissection and immunohistochemistry techniques, as well as fluorescence imaging and image processing.

Key Publications

Evangelisti E., Gogleva G., Hainaux H., Doumane M., Tulin F., Quan C., Yunusov T., Floch K., Schornack S. (2017) Time-resolved dual transcriptomics reveal early induced Nicotiana benthamiana root genes and conserved infection-promoting Phytophthora palmivora effectors. BMC Biol.

Research Laboratory Coordinator
Dr Temur  Yunusov

Contact Details

Sainsbury Laboratory
University of Cambridge
Bateman Street