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Dr Pau Formosa-Jordan

Dr Pau Formosa-Jordan

Herchel Smith Post Doctoral Research Fellow

Sainsbury Laboratory
University of Cambridge
47 Bateman Street

Cambridge CB2 1LR
Office Phone: +44(0)1223 761100

Biography:

I received my degree in Physics (2006) and Masters in Biophysics (2007) at the University of Barcelona. I did my PhD in Physics (2013) at the same institution, under the supervision of Dr Marta Ibañes and Prof Jose María Sancho. During this PhD I investigated different problems of pattern formation in animal and plant tissues from a theoretical perspective, in collaboration with experimental groups. In May 2014 I joined SLCU as a postdoctoral researcher.

Research Interests

In my current research at the SLCU, I am particularly interested in tackling different aspects of cell signalling and patterning at the tissue, cellular and subcellular levels. To do so, I am using combined theoretical and experimental approaches involving mathematical modelling and time lapse microscopy of fluorescent markers in plant tissues and in cell cultures. 

Key Publications

 

H M Meyer*, J Teles*, P Formosa-Jordan*, Y Refahi, R San- Bento, G Ingram, H Jönsson, J CW Locke and A HK Roeder (2017) Fluctuations of the transcription factor ATML1 generate the pattern of giant cells in the Arabidopsis sepal. eLife, 10.7554/eLife.19131.  Link, PDF, Figs and Supp Figs (* joint first authors)

N Fàbregas*, P Formosa-Jordan*, A Confraria*, R Siligato, J M Alonso, R Swarup, M J Bennett, A Pekka Mähönen, A I Caño-Delgado and M Ibañes (2015) Influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana. PLoS Genetics, 11(4): e1005183. doi:10.1371/journal.pgen.1005183 Link, PDF, Supp Info  (* joint first authors)

J Petrovic*, P Formosa-Jordan*, JC Luna-Escalante, G Abelló, M Ibañes, J Neves and F Giraldez (2014) Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear. Development, 141, 2313-2324. Link (* joint first authors) 

P Formosa-Jordan and M Ibañes (2014) Competition in Notch Signaling with Cis Enriches Cell Fate Decisions. PLoS ONE, vol. 9(4) p. e95744. Link

P Formosa-Jordan (2013) Pattern formation through lateral inhibition mediated by Notch signaling (PhD Thesis). LinkPDF
 

P Formosa-Jordan, M Ibañes, S Ares and JM Frade (2012) Regulation of neuronal differentiation at the neurogenic wavefront. Development, 139, 2321-2329. LinkPDF

P Formosa-Jordan and M Ibañes (2009) Diffusible ligand and lateral inhibition dynamics for pattern formation. Journal of Statistical Mechanics: Theory and Experiment P03019. LinkPDF


Book Chapters and Reviews

N Fàbregas*, P Formosa-Jordan*, M Ibañes and A I Caño-Delgado (2017) Experimental and Theoretical Methods to Approach the Study of Vascular Patterning in the Plant Shoot. In "Xylem - Methods and Protocols", Methods in Molecular Biology, ed. M. de Lucas and J. Peter Etchells. Springer Science+Business Media, New York.  Link (* joint first authors)

P Formosa-Jordan and D Sprinzak (2014) Modeling Notch signaling: a practical tutorial. In "Notch Signaling - Methods and Protocols", Methods in Molecular Biology, 1187:285-310 ed. H. Bellen and S. Yamamoto. Springer Science+Business Media, New York.  Link

P Formosa-Jordan, M Ibañes, S Ares and JM Frade (2013) Lateral inhibition and neurogenesis: novel aspects in motion. International Journal of Developmental Biology, 57:341-350. Link