skip to content

Sainsbury Laboratory


Research Interests

Plants deal with microbes from germination to decay. While most of these contacts have no consequence for both organisms, in some cases plant tissues are invaded by detrimental microorganisms, leading to disease. Conversely, beneficial microbes may develop symbiotic interactions with plants. In both cases, host-microbe communication is supported by complex molecular exchanges. Extensive studies performed on plant pathogens led to the identification of small secreted molecules termed effectors that act as key elements of this molecular dialog. Effectors are mainly known for their ability to suppress plant immunity. However, recent reports suggest that some of them may also interfere with hormone physiology and plant development, and effectors were also identified during symbiotic interactions. These emerging functions warrant further investigation.

I recently completed my PhD in the Agrobiotech Institute of Sophia-Antipolis (France, 06) where I studied effectors expressed during the infection of the first root cells by the oomycete Phytophthora parasitica (Attard et al, submitted). One of these effectors, Penetration-Specific Effector 1 (PSE1), led to various root and root hair phenotypes when expressed in Arabidopsis thaliana. Based on these phenotypes, we found that PSE1 interferes with auxin physiology and partitioning of auxin efflux carriers PIN4 and PIN7 at the root tip (Evangelisti et al, 2013).

I have joined the Schornack group in order to study effectors from the oomycete Phytophthora palmivora during interaction with Nicotiana benthamiana and Arabidopsis thaliana. My objective is to identify effectors that interfere with plant development and investigate their possible role in symbiosis establishment.

Constitutive expression of pathogen effectors in Arabidopsis thaliana (upper pane) and Nicotiana benthamiana (lower pane) results in subtle alterations of plant development.


Key Publications

Evangelisti E., Gogleva G., Hainaux H., Doumane M., Tulin F., Quan C., Yunusov T., Floch K., Schornack S. (2017) Time-resolved dual transcriptomics reveal early induced Nicotiana benthamiana root genes and conserved infection-promoting Phytophthora palmivora effectors. BMC Biol.

Evangelisti E, Rey, T, Schornack S. (2014) Cross-interference of plant development and plant-microbe interactions. Curr Opin Plant Biol. 20:118–126

Attard, A., Evangelisti, E., Kebdani-Minet, N., Panabières, F., Deleury, E., Maggio, C., Ponchet, M., and Gourgues, M. (2014). Transcriptome dynamics of Arabidopsis thaliana root penetration by the oomycete pathogen Phytophthora parasiticaBMC Genomics 15, 538.

Evangelisti E, Govetto B, Minet-Kebdani N, Kuhn ML, Attard A, Ponchet M, Panabières F, Gourgues M (2013). The Phytophthora parasitica RXLR effector penetration-specific effector 1 favours Arabidopsis thaliana infection by interfering with auxin physiologyNew Phytol.  199(2):476-89.

Jaouannet M, Magliano M, Arguel MJ, Gourgues M, Evangelisti E, Abad P, Rosso MN (2013). The root-knot nematode calreticulin Mi-CRT is a key effector in plant defense suppressionMol Plant Microbe Interact. 26(1):97-105.

Horchani F, Prévot M, Boscari A, Evangelisti E, Meilhoc E, Bruand C, Raymond P, Boncompagni E, Aschi-Smiti S, Puppo A, Brouquisse R (2011). Both plant and bacterial nitrate reductases contribute to nitric oxide production in Medicago truncatula nitrogen-fixing nodules. Plant Physiol. 155(2):1023-36.

Research Associate
Dr Edouard  Evangelisti

Contact Details

Sainsbury Laboratory
47 Bateman Street