Dr Jayne Griffiths
- Research Associate
- Jones Group Lab Manager
Contact
Location
- Sainsbury Laboratory
- Bateman Street, Cambridge, CB2 1LR
About
I am the Jones Group Lab Manager and a Research Associate. The importance of the phytohormone gibberellin for plant growth and development is well recognised. Understanding where and how GA is distributed is the first step to understanding how GA signalling leads to such a diverse range of responses. I am fascinated by cellular GA dynamics in the dark grown hypocotyl and how these spatiotemporal patterns of GA arise.
I have always been interested the development of plants and have covered many aspects of plant development during my research career. Firstly I completed my PhD at Rothamsted Research under the supervision of Peter Hedden, Steve Thomas and Andy Phillips where I identified early GA regulated genes, one of which was identified as the GA receptor GID1. I followed up my research on GA by moving to another phytohormone, this time investigating ABA and dormancy in CSIRO, Canberra. After a short position back at Rothamsted Research, where I was following up lines of research founded during my PhD, I moved to the University of Edinburgh where I was involved in a large multidisciplinary project researching the effects of the circadian clock and temperature on plant development. When I moved to the Sainsbury Laboratory Cambridge University, I became involved in lab management. I was the Paszkowski Lab Manager whilst simultaneously researching epigenetic effects on plant development and stress induced transposable elements.
Research
Research interests
- Plant hormones
- Giberellin
- Biosensors
I am exploring how the distribution of GA in the dark grown hypocotyl occurs. An etiolated Arabidopsis hypocotyl has low GA in the apical hook (small cells) and high GA in the hypocotyl (elongated cells). In order to understand how this distribution of GA is formed I am employing a range of techniques including live cell imaging of the nlsGPS biosensor in light pathway mutants, Y1H screens and RNA-seq.