Heather McLaughlin Research Portfolio
Dr Heather McLaughlin
Research Associate
Jönsson Group
Email: heather.mclaughlin@slcu.cam.ac.uk
Research interests
I am primarily interested in the phytohormone mediated regulation of plant growth and morphogenesis. I am especially interested in understanding the roles of “non-canonical” auxin pathways in processes which have traditionally been linked to canonical auxin signalling, such as the regulation of phyllotaxis and the emergence of organ primordia on the flanks of the meristem. I am utilising a range of methods in my research including genetic studies, confocal microscopy, and computational methods to quantitatively characterise phenotypes in the shoot apical meristems of a range of auxin signalling mutants. I am also interested in the interplay between auxin and cytokinin.
An interesting question is how alterations in the size or activity of the shoot apical meristem within mutants impact the gross morphology of a plant, and this is an area I am actively exploring by time lapse imaging the growth of plant rosettes.
Heather M. McLaughlin, Bhavani Natarajan, Lars Østergaard (2022), Canonical and ETT-mediated auxin signalling pathways synergistically promote gynoecium development in Arabidopsis thaliana. bioRxiv 2023.03.02.530771; doi: https://doi.org/10.1101/2023.03.02.530771
Deb, J., Bland, H. M. & Østergaard, L. (2018), Developmental cartography: coordination via hormonal and genetic interactions during gynoecium formation. Current Opinion in Plant Biology, 41: 54-60.
Kuhn, A., Ramans Harborough, S., McLaughlin, H. M., Natarajan, B., Verstraeten, I., Friml, J., Kepinski, S. & Østergaard, L. (2020), Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. eLife, 9:e51787, DOI: 10.7554/eLife.51787.
McLaughlin, H. M., Ang, A. C. H. & Østergaard, L. (2021), Noncanonical auxin signaling, Cold Spring Harbour Perspectives in Biology. DOI: 10.1101/cshperspect.a039917