skip to primary navigationskip to content
 

Dr Sabine Brumm

Dr Sabine Brumm

Research Associate

Sainsbury Laboratory
University of Cambridge
47 Bateman Street
Cambridge CB2 1LR

Biography:

I completed my MSc in Plant Molecular Biology in the laboratory of Marcelo Desimone (National University of Cordoba, Argentina) in cooperation with the Center for Plant Molecular Biology (ZMBP) in Tuebingen. In Cordoba I studied the subcellular localisation of two putative hormone transporters in Arabidopsis thaliana and Soybean. Afterwards, I re-joined the ZMBP as a PhD student in the group of Gerd Juergens. The group focuses their research on molecular mechanisms underlying the directed transport of proteins in plant cells. As part of my PhD project I analysed how small ARF-GTPases and their respective ARF-GEFs contribute to the specificity of vesicle formation in Arabidopsis thaliana. After several years of Arabidopsis research, I wanted to broaden my field of expertise, so in July 2019 I joined the Schornack group where I have the opportunity to work on various plant and microbial organisms.

Research Interests

Since July 2019 I have been working as a Postdoctoral Research Associate in the group of Sebastian Schornack. My scientific goal is to contribute to a better understanding of the regulatory mechanism underlying plant-microbe interactions by combining scientific approaches from the vesicle trafficking and plant-microbe interaction research fields. Already during my bachelor studies I was fascinated by the various abilities of plants as sessile organisms to adapt and interact with their environment. The Schornack group is interested in the identification of conserved molecular mechanism underlying plant-microbial interactions and to understand the developmental processes enabling beneficial and detrimental organisms to enter plant cells. Directed protein transport in form of vesicle trafficking is an essential process in multicellular organisms and enables interactions in form of communication and responses between plants and their partners.

Key Publications

Richter, S., Kientz, M., Brumm, S., Nielsen, M.E., Park, M., Gavidia, R., Krause, C., Voss, U., Beckmann, H., Mayer, U., et al. (2014). Delivery of endocytosed proteins to the cell-division plane requires change of pathway from recycling to secretion. Elife 3, e02131.

 

Singh, M.K., Krüger, F., Beckmann, H., Brumm, S., Vermeer, J.E.M., Munnik, T., Mayer, U., Stierhof, Y.D., Grefen, C., Schumacher, K., et al. (2014). Protein Delivery to Vacuole Requires SAND Protein- Dependent Rab GTPase Conversion for MVB-Vacuole Fusion. Current Biology 24, 1383-1389.