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Dr Weibing Yang

Dr Weibing Yang

Post Doctoral Research Associate

Sainsbury Laboratory
University of Cambridge
47 Bateman Street

Cambridge CB2 1LR
Office Phone: +44(0)1223 761100

Research Interests

In plants active division and differentiation of stem cells and their progenitors in the meristems lead to continuous formation of new tissues and organs, ensuring developmental plasticity in a changing environment. I use the Arabidopsis shoot apical meristem (SAM) as a model to study cell division. My research interests focus on the chemical and physical changes during cell division and how these cellular dynamics are integrated with plant morphogenesis. Currently I am applying multidisciplinary approaches including real-time confocal live imaging, RNA fluorescence in situ hybridisation (FISH), and computational modelling to dissect the molecular network that triggers and maintains cell cycle progression and de novo cell wall formation in meristematic cells. 

WeibingYang1

Active cell division in the Arabidopsis shoot apical meristem and developing flower primordia. Cell walls (in magenta) are revealed by Propidium Iodide staining. Dividing cells (in green) are shown by the mitosis marker CYCB1;1-GFP.

Key Publications

Yang, W., Wightman, R., Meyerowitz, E.M. (2017). Cell Cycle Control by Nuclear Sequestration of CDC20 and CDH1 mRNA in Plant Stem Cells. Mol. Cell 68:1108-1119.

Prunet, N., Yang, W., Das, P., Meyerowitz, E.M., and Jack, T.P. (2017). SUPERMAN prevents class B gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers. Proc. Natl. Acad. Sci. USA 114:7166-7171.

Yang, W., Schuster, C., Beahan, C.T., Charoensawan, V., Peaucelle, A., Bacic, A., Doblin, M.S., Wightman, R., and Meyerowitz, E.M. (2016). Regulation of Meristem Morphogenesis by Cell Wall Synthases in Arabidopsis. Curr. Biol. 26:1404-1415.

Yang, W., Gao, M., Yin, X., Liu, J., Xu, Y., Zeng, L., Li, Q., Zhang, S., Wang, J., Zhang, X., and He, Z. (2013). Control of rice embryo development, shoot apical meristem maintenance, and grain yield by a novel cytochrome P450. Mol. Plant 6:1945-1960.

Yang, W., Ren, S., Zhang, X., Gao, M., Ye, S., Qi, Y., Zheng, Y., Wang, J., Zeng, L., Li, Q., Huang, S., and He, Z. (2011). BENT UPPERMOST INTERNODE1 encodes the class II formin FH5 crucial for actin organization and rice development. Plant Cell 23: 661-680.