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Sainsbury Laboratory

Read more at: Zoe Nahas

Zoe Nahas

During my undergraduate, I worked in Liam Dolan’s lab on the role of miRNAs in the development of the model liverwort Marchantia polymorpha. My research project was two-fold: (i) the general and sex-specific importance of miRNAs in the vegetative to reproductive phase transitions, and (ii) the role of the RSL Class 1 transcription factor and its microRNA FRH1 in regulating the formation of vegetative structures.


Read more at: Dr Sally Ward

Dr Sally Ward

Research Interests



Read more at: Professor Ottoline Leyser

Professor Ottoline Leyser

*Professor Leyser is on secondment to UKRI until June 2025 and is not currently accepting any new students or research staff team members. 

Journal articles

2023

  • Tavares, H., Readshaw, A., Kania, U., de Jong, M., Pasam, RK., McCulloch, H., Ward, S., Shenhav, L., Forsyth, E. and Leyser, O., 2023. Artificial selection reveals complex genetic architecture of shoot branching and its response to nitrate supply in Arabidopsis. PLoS Genet, v. 19
    Doi: 10.1371/journal.pgen.1010863
  • Su, C., Kokosza, A., Xie, X., Pěnčík, A., Zhang, Y., Raumonen, P., Shi, X., Muranen, S., Topcu, MK., Immanen, J., Hagqvist, R., Safronov, O., Alonso-Serra, J., Eswaran, G., Venegas, MP., Ljung, K., Ward, S., Mähönen, AP., Himanen, K., Salojärvi, J., Fernie, AR., Novák, O., Leyser, O., Pałubicki, W., Helariutta, Y. and Nieminen, K., 2023. Tree architecture: A strigolactone-deficient mutant reveals a connection between branching order and auxin gradient along the tree stem. Proc Natl Acad Sci U S A, v. 120
    Doi: http://doi.org/10.1073/pnas.2308587120
  • 2022

  • Hamon-Josse, M., Villaécija-Aguilar, JA., Ljung, K., Leyser, O., Gutjahr, C. and Bennett, T., 2022. KAI2 regulates seedling development by mediating light-induced remodelling of auxin transport. New Phytol, v. 235
    Doi: http://doi.org/10.1111/nph.18110
  • Laskowski, MJ., Tiley, HC., Fang, Y., Epstein, A., Fu, Y., Ramos, R., Drummond, TJ., Heidstra, R., Bhakhri, P., Baskin, TI. and Leyser, O., 2022. The miR156 juvenility factor and PLETHORA 2 form a regulatory network and influence timing of meristem growth and lateral root emergence. Development, v. 149
    Doi: http://doi.org/10.1242/dev.199871
  • 2021

  • Abley, K., Formosa-Jordan, P., Tavares, H., Chan, EY., Afsharinafar, M., Leyser, O. and Locke, JC., 2021. An ABA-GA bistable switch can account for natural variation in the variability of Arabidopsis seed germination time. Elife, v. 10
    Doi: http://doi.org/10.7554/eLife.59485
  • Hamon-Josse, M., Villaecija-Aguilar, JA., Ljung, K., Leyser, O., Gutjahr, C. and Bennett, T., 2021. KAI2 regulates seedling development by mediating light-induced remodelling of auxin transport
    Doi: http://doi.org/10.1101/2021.05.06.443001
  • Paterlini, A., Dorussen, D., Fichtner, F., van Rongen, M., Delacruz, R., Vojnović, A., Helariutta, Y. and Leyser, O., 2021. Callose accumulation in specific phloem cell types reduces axillary bud growth in Arabidopsis thaliana. New Phytol,
    Doi: http://doi.org/10.1111/nph.17398
  • 2020

  • Oldroyd, GED. and Leyser, O., 2020. A plant's diet, surviving in a variable nutrient environment. Science, v. 368
    Doi: http://doi.org/10.1126/science.aba0196
  • Abley, K., Formosa-Jordan, P., Tavares, H., Chan, E., Leyser, O. and Locke, JCW., 2020. An ABA-GA bistable switch can account for natural variation in the variability of Arabidopsis seed germination time
    Doi: http://doi.org/10.1101/2020.06.05.135681
  • Leyser, O., 2020. The excellence question. Science, v. 370
    Doi: http://doi.org/10.1126/science.abf7125
  • 2019 (Accepted for publication)

  • Leyser, HMO., Van Rongen, M., Bennett, T. and Ticchiarelli, F., 2019 (Accepted for publication). Connective auxin transport contributes to strigolactone-mediated shoot branching control independent of the transcription factor BRC1 PLoS Genetics, v. 15
    Doi: http://doi.org/10.1371/journal.pgen.1008023
  • Conn, A., Chandrasekhar, A., Van Rongen, M., Leyser, H., Chory, J. and Navlakha, S., 2019 (Accepted for publication). Network trade-offs and homeostasis in Arabidopsis shoot architectures PLoS Computational Biology,
  • 2019

  • de Jong, M., Tavares, H., Pasam, RK., Butler, R., Ward, S., George, G., Melnyk, CW., Challis, R., Kover, PX. and Leyser, O., 2019. Natural variation in Arabidopsis shoot branching plasticity in response to nitrate supply affects fitness. PLoS Genet, v. 15
    Doi: http://doi.org/10.1371/journal.pgen.1008366
  • 2018 (Accepted for publication)

  • Leyser, HMO. and Waldie, T., 2018 (Accepted for publication). Cytokinin targets auxin transport to promote shoot branching Plant Physiology,
  • Leyser, HMO., 2018 (Accepted for publication). Structural Plasticity of D3-D14 Ubiquitin Ligase in Strigolactone Signaling Nature,
  • 2017 (Accepted for publication)

  • Leyser, HMO., 2017 (Accepted for publication). Auxin Signaling Plant Physiology,
    Doi: http://doi.org/10.1104/pp.17.00765
  • Leyser, HMO., ligerot, Y., de Saint Germain, A., Waldie, T., Troadec, C., Citerne, S., Kadakia, N., Pillot, J-P., Prigge, M., Aubert, G., Bendahmane, A., Estelle, M., Debelle, F. and Rameau, C., 2017 (Accepted for publication). The pea branching RMS2 gene encodes the PsAFB4/5 auxin receptor and is involved in an auxin-strigolactone regulation loop PLoS Genetics,
  • 2017

  • Seale, M., Bennett, T. and Leyser, O., 2017. BRC1 expression regulates bud activation potential but is not necessary or sufficient for bud growth inhibition in $\textit{Arabidopsis}$ Development, v. 144
    Doi: http://doi.org/10.1242/dev.145649
  • O'Connor, DL., Elton, S., Ticchiarelli, F., Hsia, MM., Vogel, JP. and Leyser, O., 2017. Cross-species functional diversity within the PIN auxin efflux protein family. Elife, v. 6
    Doi: http://doi.org/10.7554/eLife.31804
  • Ligerot, Y., de Saint Germain, A., Waldie, T., Troadec, C., Citerne, S., Kadakia, N., Pillot, J-P., Prigge, M., Aubert, G., Bendahmane, A., Leyser, O., Estelle, M., Debellé, F. and Rameau, C., 2017. The pea branching RMS2 gene encodes the PsAFB4/5 auxin receptor and is involved in an auxin-strigolactone regulation loop. PLoS Genet, v. 13
    Doi: http://doi.org/10.1371/journal.pgen.1007089
  • O'Connor, DL., Elton, S., Ticchiarelli, F., Hsia, MM., Vogel, J. and Leyser, O., 2017. Cross-species functional diversity within the PIN auxin efflux protein family eLife,
    Doi: http://doi.org/10.7554/eLife.31804
  • 2016

  • Liang, Y., Ward, S., Li, P., Bennett, T. and Leyser, O., 2016. SMAX1-LIKE7 Signals from the Nucleus to Regulate Shoot Development in Arabidopsis via Partially EAR Motif-Independent Mechanisms. Plant Cell, v. 28
    Doi: http://doi.org/10.1105/tpc.16.00286
  • Leyser, O., 2016. Plant development: a Special Issue. Development, v. 143
    Doi: http://doi.org/10.1242/dev.143594
  • Bennett, T., Liang, Y., Seale, M., Ward, S., Müller, D. and Leyser, O., 2016. Strigolactone regulates shoot development through a core signalling pathway. Biology Open, v. 5
    Doi: http://doi.org/10.1242/bio.021402
  • Bennett, T., Liang, Y., Seale, M., Ward, S., Mueller, D. and Leyser, O., 2016. Strigolactone regulates shoot development through a core signalling pathway Biology Open,
    Doi: http://doi.org/10.1242/bio.021402
  • Abley, K., Locke, JCW. and Leyser, HMO., 2016. Developmental mechanisms underlying variable, invariant and plastic phenotypes. Ann Bot, v. 117
    Doi: http://doi.org/10.1093/aob/mcw016
  • Bennett, T., Hines, G., van Rongen, M., Waldie, T., Sawchuk, MG., Scarpella, E., Ljung, K. and Leyser, O., 2016. Connective Auxin Transport in the Shoot Facilitates Communication between Shoot Apices. PLoS Biol, v. 14
    Doi: http://doi.org/10.1371/journal.pbio.1002446
  • 2015

  • Coudert, Y., Palubicki, W., Ljung, K., Novak, O., Leyser, O. and Jill Harrison, C., 2015. Three ancient hormonal cues co-ordinate shoot branching in a moss eLife, v. 2015
    Doi: http://doi.org/10.7554/eLife.06808.001
  • Joynson, C. and Leyser, O., 2015. The culture of scientific research. F1000Res, v. 4
    Doi: http://doi.org/10.12688/f1000research.6163.1
  • Melnyk, CW., Schuster, C., Leyser, O. and Meyerowitz, EM., 2015. A Developmental Framework for Graft Formation and Vascular Reconnection in Arabidopsis thaliana. Curr Biol, v. 25
    Doi: http://doi.org/10.1016/j.cub.2015.03.032
  • Müller, D., Waldie, T., Miyawaki, K., To, JPC., Melnyk, CW., Kieber, JJ., Kakimoto, T. and Leyser, O., 2015. Cytokinin is required for escape but not release from auxin mediated apical dominance. Plant J, v. 82
    Doi: http://doi.org/10.1111/tpj.12862
  • Müller, D., Waldie, T., Miyawaki, K., To, JPC., Melnyk, CW., Kieber, JJ., Kakimoto, T. and Leyser, O., 2015. Cytokinin is required for escape but not release from auxin mediated apical dominance Plant Journal, v. 82
    Doi: http://doi.org/10.1111/tpj.12862
  • Johnson, KL., Ramm, S., Kappel, C., Ward, S., Leyser, O., Sakamoto, T., Kurata, T., Bevan, MW. and Lenhard, M., 2015. The Tinkerbell (Tink) Mutation Identifies the Dual-Specificity MAPK Phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) as a Novel Regulator of Organ Size in Arabidopsis. PLoS One, v. 10
    Doi: http://doi.org/10.1371/journal.pone.0131103
  • Johnson, KL., Ramm, S., Kappel, C., Ward, S., Leyser, O., Sakamoto, T., Kurata, T., Bevan, MW. and Lenhard, M., 2015. Correction: The Tinkerbell (Tink) Mutation Identifies the Dual-Specificity MAPK Phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) as a Novel Regulator of Organ Size in Arabidopsis. PLoS One, v. 10
    Doi: http://doi.org/10.1371/journal.pone.0136482
  • Soundappan, I., Bennett, T., Morffy, N., Liang, Y., Stanga, JP., Abbas, A., Leyser, O. and Nelson, DC., 2015. SMAX1-LIKE/D53 Family Members Enable Distinct MAX2-Dependent Responses to Strigolactones and Karrikins in Arabidopsis. Plant Cell, v. 27
    Doi: http://doi.org/10.1105/tpc.15.00562
  • Coudert, Y., Palubicki, W., Ljung, K., Novak, O., Leyser, O. and Harrison, CJ., 2015. Three ancient hormonal cues co-ordinate shoot branching in a moss. Elife, v. 4
    Doi: http://doi.org/10.7554/eLife.06808
  • 2014

  • Bainbridge, K., Bennett, T., Crisp, P., Leyser, O. and Turnbull, C., 2014. Grafting in Arabidopsis. Methods Mol Biol, v. 1062
    Doi: http://doi.org/10.1007/978-1-62703-580-4_7
  • Bennett, T., Hines, G. and Leyser, O., 2014. Canalization: what the flux? Trends Genet, v. 30
    Doi: http://doi.org/10.1016/j.tig.2013.11.001
  • Salmon, J., Ward, SP., Hanley, SJ., Leyser, O. and Karp, A., 2014. Functional screening of willow alleles in Arabidopsis combined with QTL mapping in willow (Salix) identifies SxMAX4 as a coppicing response gene. Plant Biotechnol J, v. 12
    Doi: http://doi.org/10.1111/pbi.12154
  • Cardoso, C., Zhang, Y., Jamil, M., Hepworth, J., Charnikhova, T., Dimkpa, SON., Meharg, C., Wright, MH., Liu, J., Meng, X., Wang, Y., Li, J., McCouch, SR., Leyser, O., Price, AH., Bouwmeester, HJ. and Ruyter-Spira, C., 2014. Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs. Proc Natl Acad Sci U S A, v. 111
    Doi: http://doi.org/10.1073/pnas.1317360111
  • Bennett, T., Hines, G. and Leyser, O., 2014. Canalization: What the flux? Trends in Genetics, v. 30
    Doi: http://doi.org/10.1016/j.tig.2013.11.001
  • Waldie, T., McCulloch, H. and Leyser, O., 2014. Strigolactones and the control of plant development: lessons from shoot branching. Plant J, v. 79
    Doi: http://doi.org/10.1111/tpj.12488
  • Bennett, T., Brockington, SF., Rothfels, C., Graham, SW., Stevenson, D., Kutchan, T., Rolf, M., Thomas, P., Wong, GK-S., Leyser, O., Glover, BJ. and Harrison, CJ., 2014. Paralogous radiations of PIN proteins with multiple origins of noncanonical PIN structure. Mol Biol Evol, v. 31
    Doi: http://doi.org/10.1093/molbev/msu147
  • Salmon, J., Ward, SP., Hanley, SJ., Leyser, O. and Karp, A., 2014. Functional screening of willow alleles in Arabidopsis combined with QTL mapping in willow (Salix) identifies SxMAX4 as a coppicing response gene Plant Biotechnology Journal, v. 12
    Doi: http://doi.org/10.1111/pbi.12154
  • Cardoso, C., Zhang, Y., Jamil, M., Hepworth, J., Charnikhova, T., Dimkpa, SON., Meharg, C., Wright, MH., Liu, J., Meng, X., Wang, Y., Li, J., McCouch, SR., Leyser, O., Price, AH., Bouwmeester, HJ. and Carolien, RS., 2014. Erratum: Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (2379-2384) DOI: 10.1073/pnas.1317360111) Proceedings of the National Academy of Sciences of the United States of America, v. 111
    Doi: http://doi.org/10.1073/pnas.1405730111
  • Leyser, O., 2014. Moving beyond the GM debate. PLoS Biol, v. 12
    Doi: http://doi.org/10.1371/journal.pbio.1001887
  • de Jong, M., George, G., Ongaro, V., Williamson, L., Willetts, B., Ljung, K., McCulloch, H. and Leyser, O., 2014. Auxin and strigolactone signaling are required for modulation of Arabidopsis shoot branching by nitrogen supply. Plant Physiol, v. 166
    Doi: http://doi.org/10.1104/pp.114.242388
  • Bennett, T. and Leyser, O., 2014. Strigolactone signalling: standing on the shoulders of DWARFs. Curr Opin Plant Biol, v. 22
    Doi: http://doi.org/10.1016/j.pbi.2014.08.001
  • Bainbridge, K., Bennett, T., Crisp, P., Leyser, O. and Turnbull, C., 2014. Grafting in Arabidopsis Methods in Molecular Biology, v. 1062
    Doi: http://doi.org/10.1007/978-1-62703-580-4_7
  • Waldie, T., McCulloch, H. and Leyser, O., 2014. Strigolactones and the control of plant development: Lessons from shoot branching Plant Journal, v. 79
    Doi: http://doi.org/10.1111/tpj.12488
  • Zhang, Y., van Dijk, ADJ., Scaffidi, A., Flematti, GR., Hofmann, M., Charnikhova, T., Verstappen, F., Hepworth, J., van der Krol, S., Leyser, O., Smith, SM., Zwanenburg, B., Al-Babili, S., Ruyter-Spira, C. and Bouwmeester, HJ., 2014. Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis. Nat Chem Biol, v. 10
    Doi: http://doi.org/10.1038/nchembio.1660
  • Leyser, O. and Sedwick, C., 2014. Ottoline Leyser: the beauty of plant genetics. Interviewed by Caitlin Sedwick. J Cell Biol, v. 204
    Doi: http://doi.org/10.1083/jcb.2043pi
  • 2013

  • Shinohara, N., Taylor, C. and Leyser, O., 2013. Strigolactone can promote or inhibit shoot branching by triggering rapid depletion of the auxin efflux protein PIN1 from the plasma membrane. PLoS Biol, v. 11
    Doi: http://doi.org/10.1371/journal.pbio.1001474
  • Challis, RJ., Hepworth, J., Mouchel, C., Waites, R. and Leyser, O., 2013. A role for more axillary growth1 (MAX1) in evolutionary diversity in strigolactone signaling upstream of MAX2. Plant Physiol, v. 161
    Doi: http://doi.org/10.1104/pp.112.211383
  • Ward, SP., Salmon, J., Hanley, SJ., Karp, A. and Leyser, O., 2013. Using Arabidopsis to study shoot branching in biomass willow. Plant Physiol, v. 162
    Doi: http://doi.org/10.1104/pp.113.218461
  • 2012

  • Steinacher, A., Leyser, O. and Clayton, RH., 2012. A computational model of auxin and pH dynamics in a single plant cell. J Theor Biol, v. 296
    Doi: http://doi.org/10.1016/j.jtbi.2011.11.020
  • Stirnberg, P., Zhao, S., Williamson, L., Ward, S. and Leyser, O., 2012. FHY3 promotes shoot branching and stress tolerance in Arabidopsis in an AXR1-dependent manner. Plant J, v. 71
    Doi: http://doi.org/10.1111/j.1365-313X.2012.05038.x
  • Leyser, O., 2012. Ottoline Leyser. Curr Biol, v. 22
    Doi: http://doi.org/10.1016/j.cub.2012.02.003
  • Leyser, O., 2012. Ottoline Leyser CURRENT BIOLOGY, v. 22
    Doi: http://doi.org/10.1016/j.cub.2012.02.003
  • Stirnberg, P., Liu, J-P., Ward, S., Kendall, SL. and Leyser, O., 2012. Mutation of the cytosolic ribosomal protein-encoding RPS10B gene affects shoot meristematic function in Arabidopsis. BMC Plant Biol, v. 12
    Doi: http://doi.org/10.1186/1471-2229-12-160
  • Stepney, S., Diaconescu, A., Doursat, R., Giavitto, JL., Kowaliw, T., Leyser, O., MacLennan, B., Michel, O., Miller, JF., Nikolic, I., Spicher, A., Teuscher, C., Tufte, G., Vico, FJ. and Yamamoto, L., 2012. Gardening cyber-physical systems Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), v. 7445 LNCS
    Doi: http://doi.org/10.1007/978-3-642-32894-7_25
  • Stirnberg, P., Zhao, S., Williamson, L., Ward, S. and Leyser, O., 2012. FHY3 promotes shoot branching and stress tolerance in Arabidopsis in an AXR1-dependent manner Plant Journal, v. 71
    Doi: http://doi.org/10.1111/j.1365-313X.2012.05038.x
  • de Jong, M. and Leyser, O., 2012. Developmental plasticity in plants. Cold Spring Harb Symp Quant Biol, v. 77
    Doi: http://doi.org/10.1101/sqb.2012.77.014720
  • 2011

  • Amsen, E. and Leyser, O., 2011. An interview with Ottoline Leyser DEVELOPMENT, v. 138
    Doi: http://doi.org/10.1242/dev.075333
  • Kohlen, W., Charnikhova, T., Liu, Q., Bours, R., Domagalska, MA., Beguerie, S., Verstappen, F., Leyser, O., Bouwmeester, H. and Ruyter-Spira, C., 2011. Strigolactones are transported through the xylem and play a key role in shoot architectural response to phosphate deficiency in nonarbuscular mycorrhizal host Arabidopsis. Plant Physiol, v. 155
    Doi: http://doi.org/10.1104/pp.110.164640
  • Domagalska, MA. and Leyser, O., 2011. Signal integration in the control of shoot branching. Nat Rev Mol Cell Biol, v. 12
    Doi: http://doi.org/10.1038/nrm3088
  • Müller, D. and Leyser, O., 2011. Auxin, cytokinin and the control of shoot branching. Ann Bot, v. 107
    Doi: http://doi.org/10.1093/aob/mcr069
  • Leyser, O., 2011. Auxin, self-organisation, and the colonial nature of plants. Curr Biol, v. 21
    Doi: http://doi.org/10.1016/j.cub.2011.02.031
  • 2010

  • Lohmann, D., Stacey, N., Breuninger, H., Jikumaru, Y., Müller, D., Sicard, A., Leyser, O., Yamaguchi, S. and Lenhard, M., 2010. SLOW MOTION is required for within-plant auxin homeostasis and normal timing of lateral organ initiation at the shoot meristem in Arabidopsis. Plant Cell, v. 22
    Doi: http://doi.org/10.1105/tpc.109.071498
  • Stirnberg, P., Ward, S. and Leyser, O., 2010. Auxin and strigolactones in shoot branching: intimately connected? Biochem Soc Trans, v. 38
    Doi: http://doi.org/10.1042/BST0380717
  • Liang, J., Zhao, L., Challis, R. and Leyser, O., 2010. Strigolactone regulation of shoot branching in chrysanthemum (Dendranthema grandiflorum). J Exp Bot, v. 61
    Doi: http://doi.org/10.1093/jxb/erq133
  • Garnett, P., Steinacher, A., Stepney, S., Clayton, R. and Leyser, O., 2010. Computer simulation: the imaginary friend of auxin transport biology. Bioessays, v. 32
    Doi: http://doi.org/10.1002/bies.200900185
  • Crawford, S., Shinohara, N., Sieberer, T., Williamson, L., George, G., Hepworth, J., Müller, D., Domagalska, MA. and Leyser, O., 2010. Strigolactones enhance competition between shoot branches by dampening auxin transport. Development, v. 137
    Doi: http://doi.org/10.1242/dev.051987
  • Baskin, TI., Peret, B., Baluška, F., Benfey, PN., Bennett, M., Forde, BG., Gilroy, S., Helariutta, Y., Hepler, PK., Leyser, O., Masson, PH., Muday, GK., Murphy, AS., Poethig, S., Rahman, A., Roberts, K., Scheres, B., Sharp, RE. and Somerville, C., 2010. Shootward and rootward: peak terminology for plant polarity. Trends Plant Sci, v. 15
    Doi: http://doi.org/10.1016/j.tplants.2010.08.006
  • Leyser, O., 2010. The power of auxin in plants. Plant Physiol, v. 154
    Doi: http://doi.org/10.1104/pp.110.161323
  • Liang, Y-K., Xie, X., Lindsay, SE., Wang, YB., Masle, J., Williamson, L., Leyser, O. and Hetherington, AM., 2010. Cell wall composition contributes to the control of transpiration efficiency in Arabidopsis thaliana. Plant J, v. 64
    Doi: http://doi.org/10.1111/j.1365-313X.2010.04362.x
  • 2009

  • Leyser, O., 2009. The control of shoot branching: an example of plant information processing. Plant Cell Environ, v. 32
    Doi: http://doi.org/10.1111/j.1365-3040.2009.01930.x
  • Hayward, A., Stirnberg, P., Beveridge, C. and Leyser, O., 2009. Interactions between auxin and strigolactone in shoot branching control. Plant Physiol, v. 151
    Doi: http://doi.org/10.1104/pp.109.137646
  • Prusinkiewicz, P., Crawford, S., Smith, RS., Ljung, K., Bennett, T., Ongaro, V. and Leyser, O., 2009. Control of bud activation by an auxin transport switch. Proc Natl Acad Sci U S A, v. 106
    Doi: http://doi.org/10.1073/pnas.0906696106
  • Jones, AR., Kramer, EM., Knox, K., Swarup, R., Bennett, MJ., Lazarus, CM., Leyser, HMO. and Grierson, CS., 2009. Auxin transport through non-hair cells sustains root-hair development NAT CELL BIOL, v. 11
    Doi: http://doi.org/10.1038/ncb1815
  • 2008

  • Fitter, A., Williamson, L., Linkohr, B. and Leyser, O., 2008. Root system architecture determines fitness in an Arabidopsis mutant in competition for immobile phosphate ions but not for nitrate ions Hungarian Quarterly, v. 49
    Doi: http://doi.org/10.1098/rspb.2002.2120
  • Ongaro, V., Bainbridge, K., Williamson, L. and Leyser, O., 2008. Interactions between axillary branches of Arabidopsis. Mol Plant, v. 1
    Doi: http://doi.org/10.1093/mp/ssn007
  • Ongaro, V. and Leyser, O., 2008. Hormonal control of shoot branching. J Exp Bot, v. 59
    Doi: http://doi.org/10.1093/jxb/erm134
  • Leyser, O. and Pourquié, O., 2008. Pattern formation and developmental mechanisms. Curr Opin Genet Dev, v. 18
    Doi: http://doi.org/10.1016/j.gde.2008.08.001
  • Leyser, O., 2008. Strigolactones and shoot branching: a new trick for a young dog. Dev Cell, v. 15
    Doi: http://doi.org/10.1016/j.devcel.2008.08.008
  • 2007 (Published online)

  • Bennett, TA., Crawford, SR., Ward, SP. and Leyser, O., 2007 (Published online). Shoot Branching and Plant Architecture
    Doi: 10.1002/9780470015902.a0020122
  • 2007

  • Tanimoto, M., Jowett, J., Stirnberg, P., Rouse, D. and Leyser, O., 2007. Pax I - I partially suppresses gain-of-function mutations in Arabidopsis AXR3/IAA 17 BMC Plant Biology, v. 7
    Doi: http://doi.org/10.1186/1471-2229-7-20
  • Stirnberg, P., Furner, IJ. and Ottoline Leyser, HM., 2007. MAX2 participates in an SCF complex which acts locally at the node to suppress shoot branching. Plant J, v. 50
    Doi: http://doi.org/10.1111/j.1365-313X.2007.03032.x
  • Ongaro, V. and Leyser, O., 2007. Shoot branching in Arabidopsis COMP BIOCHEM PHYS A, v. 146
    Doi: http://doi.org/10.1016/j.cbpa.2007.01.546
  • Jones, A., Lazarus, C., Grierson, C., Kramer, E., Swarup, R., Bennett, M. and Leyser, O., 2007. The role of auxin in root-hair initiation COMP BIOCHEM PHYS A, v. 146
    Doi: http://doi.org/10.1016/j.cbpa.2007.01.556
  • Tanimoto, M., Jowett, J., Stirnberg, P., Rouse, D. and Leyser, O., 2007. pax1-1 partially suppresses gain-of-function mutations in Arabidopsis AXR3/IAA17. BMC Plant Biol, v. 7
    Doi: http://doi.org/10.1186/1471-2229-7-20
  • Mouchel, CF. and Leyser, O., 2007. Novel phytohormones involved in long-range signaling. Curr Opin Plant Biol, v. 10
    Doi: http://doi.org/10.1016/j.pbi.2007.08.005
  • 2006

  • Bennett, T. and Leyser, O., 2006. Response to Prof Tomescu [2] Plant Molecular Biology, v. 62
    Doi: http://doi.org/10.1007/s11103-006-9053-7
  • Xie, XD., Wang, YB., Williamson, L., Holroyd, GH., Tagliavia, C., Murchie, E., Theobald, J., Knight, MR., Davies, WJ., Leyser, HMO. and Hetherington, AM., 2006. The identification of genes involved in the stomatal response to reduced atmospheric relative humidity CURR BIOL, v. 16
    Doi: http://doi.org/10.1016/j.cub.2006.03.028
  • Bennett, T. and Leyser, O., 2006. Comment on "Something on the side: axillary meristems and plant development." by Tom Bennett and Ottoline Leyser, Plant Molecular Biology 60 (2006) 843-854 - Response to Prof Tomescu PLANT MOL BIOL, v. 62
    Doi: http://doi.org/10.1007/s11103-006-9053-7
  • Bennett, T., Sieberer, T., Willett, B., Booker, J., Luschnig, C. and Leyser, O., 2006. The Arabidopsis MAX pathway controls shoot branching by regulating auxin transport. Curr Biol, v. 16
    Doi: http://doi.org/10.1016/j.cub.2006.01.058
  • Sieberer, T. and Leyser, O., 2006. Plant science. Auxin transport, but in which direction? Science, v. 312
    Doi: http://doi.org/10.1126/science.1127659
  • Bennett, T. and Leyser, O., 2006. Something on the side: axillary meristems and plant development. Plant Mol Biol, v. 60
    Doi: http://doi.org/10.1007/s11103-005-2763-4
  • Bainbridge, K., Bennett, T., Turnbull, C. and Leyser, O., 2006. Grafting. Methods Mol Biol, v. 323
    Doi: http://doi.org/10.1385/1-59745-003-0:39
  • Leyser, O., 2006. Dynamic integration of auxin transport and signalling. Curr Biol, v. 16
    Doi: http://doi.org/10.1016/j.cub.2006.05.014
  • Sieberer, T. and Leyser, O., 2006. Auxin transport, but in which direction? Science, v. 312
    Doi: http://doi.org/10.1126/science.1127659
  • 2005

  • Swarup, R., Kramer, EM., Perry, P., Knox, K., Leyser, HMO., Haseloff, J., Beemster, GTS., Bhalerao, R. and Bennett, MJ., 2005. Root gravitropism requires lateral root cap and epidermal cells for transport and response to a mobile auxin signal NAT CELL BIOL, v. 7
    Doi: http://doi.org/10.1038/ncb1316
  • Booker, J., Sieberer, T., Wright, W., Williamson, L., Willett, B., Stirnberg, P., Turnbull, C., Srinivasan, M., Goddard, P. and Leyser, O., 2005. MAX1 encodes a cytochrome P450 family member that acts downstream of MAX3/4 to produce a carotenoid-derived branch-inhibiting hormone. Dev Cell, v. 8
    Doi: http://doi.org/10.1016/j.devcel.2005.01.009
  • Kepinski, S. and Leyser, O., 2005. Plant development: auxin in loops. Curr Biol, v. 15
    Doi: http://doi.org/10.1016/j.cub.2005.03.012
  • McSteen, P. and Leyser, O., 2005. Shoot branching. Annu Rev Plant Biol, v. 56
    Doi: http://doi.org/10.1146/annurev.arplant.56.032604.144122
  • Tatematsu, K., Ward, S., Leyser, O., Kamiya, Y. and Nambara, E., 2005. Identification of cis-elements that regulate gene expression during initiation of axillary bud outgrowth in Arabidopsis. Plant Physiol, v. 138
    Doi: http://doi.org/10.1104/pp.104.057984
  • Kepinski, S. and Leyser, O., 2005. The Arabidopsis F-box protein TIR1 is an auxin receptor. Nature, v. 435
    Doi: http://doi.org/10.1038/nature03542
  • Leyser, O., 2005. Auxin distribution and plant pattern formation: how many angels can dance on the point of PIN? Cell, v. 121
    Doi: http://doi.org/10.1016/j.cell.2005.06.005
  • Leyser, O., 2005. The fall and rise of apical dominance. Curr Opin Genet Dev, v. 15
    Doi: http://doi.org/10.1016/j.gde.2005.06.010
  • Yamazoe, A., Hayashi, K-I., Kepinski, S., Leyser, O. and Nozaki, H., 2005. Characterization of terfestatin A, a new specific inhibitor for auxin signaling. Plant Physiol, v. 139
    Doi: http://doi.org/10.1104/pp.105.068924
  • Bainbridge, K., Sorefan, K., Ward, S. and Leyser, O., 2005. Hormonally controlled expression of the Arabidopsis MAX4 shoot branching regulatory gene. Plant J, v. 44
    Doi: http://doi.org/10.1111/j.1365-313X.2005.02548.x
  • 2004

  • Ward, SP. and Leyser, O., 2004. Shoot branching. Curr Opin Plant Biol, v. 7
    Doi: http://doi.org/10.1016/j.pbi.2003.10.002
  • Booker, J., Auldridge, M., Wills, S., McCarty, D., Klee, H. and Leyser, O., 2004. MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule. Curr Biol, v. 14
    Doi: http://doi.org/10.1016/j.cub.2004.06.061
  • Kepinski, S. and Leyser, O., 2004. Auxin-induced SCFTIR1-Aux/IAA interaction involves stable modification of the SCFTIR1 complex. Proc Natl Acad Sci U S A, v. 101
    Doi: http://doi.org/10.1073/pnas.0402868101
  • Ward, SP. and Leyser, O., 2004. A TRANSCRIPTOMICS BASED APPROACH TO STUDYING BUD DORMANCY IN ARABIDOPSIS ACTA PHYSIOL PLANT, v. 26
  • 2003

  • Booker, J., Chatfield, S. and Leyser, O., 2003. Auxin acts in xylem-associated or medullary cells to mediate apical dominance. Plant Cell, v. 15
    Doi: http://doi.org/10.1105/tpc.007542
  • Sorefan, K., Booker, J., Haurogné, K., Goussot, M., Bainbridge, K., Foo, E., Chatfield, S., Ward, S., Beveridge, C., Rameau, C. and Leyser, O., 2003. MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea. Genes Dev, v. 17
    Doi: http://doi.org/10.1101/gad.256603
  • Knox, K., Grierson, CS. and Leyser, O., 2003. AXR3 and SHY2 interact to regulate root hair development. Development, v. 130
    Doi: http://doi.org/10.1242/dev.00659
  • Leyser, O., 2003. Regulation of shoot branching by auxin. Trends Plant Sci, v. 8
    Doi: http://doi.org/10.1016/j.tplants.2003.09.008
  • Kepinski, S. and Leyser, O., 2003. Plant development: an axis of auxin. Nature, v. 426
    Doi: http://doi.org/10.1038/426132b
  • Kepinski, S. and Leyser, O., 2003. SCF-mediated proteolysis and negative regulation in ethylene signaling. Cell, v. 115
    Doi: http://doi.org/10.1016/s0092-8674(03)00978-4
  • Kepinski, S. and Leyser, O., 2003. An axis of auxin Nature, v. 426
    Doi: http://doi.org/10.1038/426132b
  • 2002

  • Kepinski, S. and Leyser, O., 2002. Ubiquitination and auxin signaling: a degrading story. Plant Cell, v. 14 Suppl
    Doi: http://doi.org/10.1105/tpc.010447
  • Leyser, O., 2002. Molecular genetics of auxin signaling. Annu Rev Plant Biol, v. 53
    Doi: http://doi.org/10.1146/annurev.arplant.53.100301.135227
  • Fitter, A., Williamson, L., Linkohr, B. and Leyser, O., 2002. Root system architecture determines fitness in an Arabidopsis mutant in competition for immobile phosphate ions but not for nitrate ions. Proc Biol Sci, v. 269
    Doi: http://doi.org/10.1098/rspb.2002.2120
  • Beale, M., Dupree, P., Lilley, K., Beynon, J., Trick, M., Clarke, J., Bevan, M., Bancroft, I., Jones, J., May, S., van de Sande, K. and Leyser, O., 2002. GARNet, the Genomic Arabidopsis Resource Network TRENDS PLANT SCI, v. 7
  • Stirnberg, P., van de Sande, K. and Leyser, HMO., 2002. MAX1 and MAX2 control shoot lateral branching in Arabidopsis DEVELOPMENT, v. 129
  • Turnbull, CGN., Booker, JP. and Leyser, HMO., 2002. Micrografting techniques for testing long-distance signalling in Arabidopsis PLANT J, v. 32
  • Linkohr, BI., Williamson, LC., Fitter, AH. and Leyser, HMO., 2002. Nitrate and phosphate availability and distribution have different effects on root system architecture of Arabidopsis PLANT J, v. 29
  • 2001

  • Leyser, O., 2001. Auxin signalling: the beginning, the middle and the end. Curr Opin Plant Biol, v. 4
    Doi: http://doi.org/10.1016/s1369-5266(00)00189-8
  • Gray, WM., Kepinski, S., Rouse, D., Leyser, O. and Estelle, M., 2001. Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins. Nature, v. 414
    Doi: http://doi.org/10.1038/35104500
  • Williamson, LC., Ribrioux, SPCP., Fitter, AH. and Leyser, HMO., 2001. Phosphate availability regulates root system architecture in Arabidopsis PLANT PHYSIOL, v. 126
  • Ramos, JA., Zenser, N., Leyser, O. and Callis, J., 2001. Rapid Degradation of Auxin/Indoleacetic Acid Proteins Requires Conserved Amino Acids of Domain II and Is Proteasome Dependent The Plant Cell, v. 13
    Doi: 10.2307/3871512
  • Leyser, O., 2001. Auxin CURR BIOL, v. 11
  • Cline, MG., Chatfield, SP. and Leyser, O., 2001. NAA restores apical dominance in the axr3-1 mutant of Arabidopsis thaliana ANN BOT-LONDON, v. 87
    Doi: http://doi.org/10.1006/anbo.2000.1298
  • Leyser, O., 2001. Summitting the Arabidopsis genome. Trends Genet, v. 17
    Doi: http://doi.org/10.1016/s0168-9525(01)02264-8
  • Ramos, JA., Zenser, N., Leyser, O. and Callis, J., 2001. Rapid degradation of auxin/indoleacetic acid proteins requires conserved amino acids of domain II and is proteasome dependent. Plant Cell, v. 13
    Doi: http://doi.org/10.1105/tpc.010244
  • 2000

  • Worley, CK., Zenser, N., Ramos, J., Rouse, D., Leyser, O., Theologis, A. and Callis, J., 2000. Degradation of Aux/IAA proteins is essential for normal auxin signalling. Plant J, v. 21
    Doi: http://doi.org/10.1046/j.1365-313x.2000.00703.x
  • Leyser, O., 2000. Mutagenesis. Methods Mol Biol, v. 141
    Doi: http://doi.org/10.1385/1-59259-067-5:133
  • Leyser, O. and Deng, XW., 2000. Cell signalling and gene regulation - New directions in plant signalling - Editorial overview CURR OPIN PLANT BIOL, v. 3
  • van de Sande, K. and Leyser, O., 2000. Functional genomics at the Arabidopsis meeting. Yeast, v. 17
    Doi: http://doi.org/10.1002/1097-0061(20000930)17:3<235::AID-YEA36>3.0.CO;2-X
  • Collett, CE., Harberd, NP. and Leyser, O., 2000. Hormonal interactions in the control of Arabidopsis hypocotyl elongation. Plant Physiol, v. 124
    Doi: http://doi.org/10.1104/pp.124.2.553
  • Chatfield, SP., Stirnberg, P., Forde, BG. and Leyser, O., 2000. The hormonal regulation of axillary bud growth in Arabidopsis. Plant J, v. 24
    Doi: http://doi.org/10.1046/j.1365-313x.2000.00862.x
  • 1999

  • Leyser, O., 1999. Plant hormones: ins and outs of auxin transport. Curr Biol, v. 9
    Doi: http://doi.org/10.1016/s0960-9822(99)80033-5
  • Stirnberg, P., Chatfield, SP. and Leyser, HMO., 1999. AXR1 acts after lateral bud formation to inhibit lateral bud growth in Arabidopsis PLANT PHYSIOL, v. 121
  • Leyser, O. and Berleth, T., 1999. A molecular basis for auxin action. Semin Cell Dev Biol, v. 10
    Doi: http://doi.org/10.1006/scdb.1999.0288
  • Sabatini, S., Beis, D., Wolkenfelt, H., Murfett, J., Guilfoyle, T., Malamy, J., Benfey, P., Leyser, O., Bechtold, N., Weisbeek, P. and Scheres, B., 1999. An auxin-dependent distal organizer of pattern and polarity in the Arabidopsis root. Cell, v. 99
    Doi: http://doi.org/10.1016/s0092-8674(00)81535-4
  • 1998

  • Leyser, HMO., 1998. Plant hormones CURR BIOL, v. 8
  • Rouse, D., Mackay, P., Stirnberg, P., Estelle, M. and Leyser, O., 1998. Changes in auxin response from mutations in an AUX/IAA gene. Science, v. 279
    Doi: http://doi.org/10.1126/science.279.5355.1371
  • Leyser, O., 1998. Auxin signalling: protein stability as a versatile control target. Curr Biol, v. 8
    Doi: http://doi.org/10.1016/s0960-9822(98)70193-9
  • Leyser, O. and Fitter, A., 1998. Roots are branching out in patches TRENDS PLANT SCI, v. 3
  • 1997

  • O'Donnell, PJ., Calvert, C., Atzorn, R., Wasternack, C., Leyser, HMO. and Bowles, DJ., 1997. Ethylene and the wound response Trends in Plant Science, v. 2
    Doi: http://doi.org/10.1016/S1360-1385(97)88388-4
  • Leyser, O., 1997. Auxin: Lessons from a mutant weed PHYSIOL PLANTARUM, v. 100
  • 1996

  • O'Donnell, PJ., Calvert, C., Atzorn, R., Wasternack, C., Leyser, HMO. and Bowles, DJ., 1996. Ethylene as a Signal Mediating the Wound Response of Tomato Plants. Science, v. 274
    Doi: http://doi.org/10.1126/science.274.5294.1914
  • Leyser, HMO., Pickett, FB., Dharmasiri, S. and Estelle, M., 1996. Mutations in the AXR3 gene of Arabidopsis result in altered auxin response including ectopic expression from the SAUR-AC1 promoter PLANT J, v. 10
  • 1993

  • LEYSER, HMO., LINCOLN, CA., TIMPTE, C., LAMMER, D., TURNER, J. and ESTELLE, M., 1993. ARABIDOPSIS AUXIN-RESISTANCE GENE-AXR1 ENCODES A PROTEIN RELATED TO UBIQUITIN-ACTIVATING ENZYME-E1 NATURE, v. 364
  • LEYSER, O., LINCOLN, C., TIMPTE, C., TURNER, J., LAMMER, D. and ESTELLE, M., 1993. MOLECULAR CHARACTERIZATION OF THE AXR1 GENE OF ARABIDOPSIS-THALIANA J CELL BIOCHEM,
  • 1992

  • LEYSER, HMO. and FURNER, IJ., 1992. CHARACTERIZATION OF 3 SHOOT APICAL MERISTEM MUTANTS OF ARABIDOPSIS-THALIANA DEVELOPMENT, v. 116
  • Kilby, NJ., Leyser, HM. and Furner, IJ., 1992. Promoter methylation and progressive transgene inactivation in Arabidopsis. Plant Mol Biol, v. 20
    Doi: http://doi.org/10.1007/BF00029153
  • Theses / dissertations

    2021 (No publication date)

  • Paterlini, A., 2021 (No publication date). A multiscale study of plasmodesmata: from channel ultrastructure to plant architecture
  • Datasets

    2021 (No publication date)

  • Abley, K., Tavares, H., Formosa-Jordan, P., Chan, EYT., Afsharinafar, M., Leyser, O. and Locke, J., 2021 (No publication date). Data supporting 'An ABA-GA bistable switch can account for natural variation in the variability of Arabidopsis seed germination time', Abley & Formosa-Jordan et al., eLife (2021)
  • 2019 (No publication date)

  • Van Rongen, M., Bennett, T., Ticchiarelli, F. and Leyser, H., 2019 (No publication date). Research data supporting "Connective auxin transport contributes to strigolactone-mediated shoot branching control independent of BRC1"
  • 2018 (No publication date)

  • De Jong, M., Monteiro Pais Tavares, H., Pasam, R., Butler, R., Ward, S., George, G., Melnyk, C., Challis, R., Kover, PX. and Leyser, HMO., 2018 (No publication date). Research Data Supporting "Natural variation in Arabidopsis shoot branching plasticity in response to nitrate supply affects fitness"
  • 2016 (No publication date)

  • Bennett, T., van, RM., Ljung, K., Waldie, T. and Leyser, O., 2016 (No publication date). Research data supporting 'Connective auxin transport in the shoot facilitates communication between shoot apices'.
  • Internet publications

    2020

  • Paterlini, A., Dorussen, D., Fichtner, F., van Rongen, M., Delacruz, R., Vojnović, A., Helariutta, Y. and Leyser, O., 2020. Blocking plasmodesmata in specific phloem cell types reduces axillary bud growth in<i>Arabidopsis thaliana</i>
    Doi: http://doi.org/10.1101/2020.12.28.424434
  • Book chapters

    2019

  • Leyser, O. and Wiseman, H., 2019. Integrative Biology: Parts, Wholes, Levels and Systems
    Doi: http://doi.org/10.1142/9789811207495_0002
  • 2014

  • Bennett, T. and Leyser, O., 2014. The auxin question: A philosophical overview
    Doi: http://doi.org/10.1007/978-3-7091-1526-8_1
  • 2006

  • Bainbridge, K., Bennett, T., Turnbull, C. and Leyser, O., 2006. Grafting
    Doi: http://doi.org/10.1385/1-59745-003-0:39
  • 2000

  • Leyser, O., 2000. Mutagenesis
    Doi: http://doi.org/10.1385/1-59259-067-5:133
  • Conference proceedings

    2017

  • Leyser, O., 2017. Signal integration and the bud activation switch MECHANISMS OF DEVELOPMENT, v. 145
    Doi: http://doi.org/10.1016/j.mod.2017.04.559
  • Leyser, O., 2017. Dual mode strigolactone signalling and the bud activation switch FEBS JOURNAL, v. 284
  • 2009

  • Hepworth, J., Mouchel, C. and Leyser, O., 2009. The evolution of a plant branching hormone MECHANISMS OF DEVELOPMENT, v. 126
    Doi: http://doi.org/10.1016/j.mod.2009.06.687
  • 1999

  • Ribrioux, S., Williamson, L., Fitter, AH. and Leyser, HMO., 1999. Phosphate control of root system architecture in Arabidopsis PHOSPHORUS IN PLANT BIOLOGY: REGULATORY ROLES IN MOLECULAR, CELLULAR, ORGANISMIC, AND ECOSYSTEM PROCESSES, v. 19
  • Books

    2017

  • Leyser, O., 2017. Foreword
    Doi: http://doi.org/10.1016/B978-0-12-811562-6.06001-1
  • 2016

  • Wild-Wood, E., 2016. Foreword
  • 2003

  • Leyser, O. and Day, S., 2003. Mechanisms in plant development