The shoot apical meristem (SAM) is a cluster of stem cells responsible for the generation of all above-ground plant tissues. It is regulated by a complex system of transcription factors (TFs), signalling peptides and hormones. WUSHEL (WUS) is the TF which defines stem cell identity in Arabidopsis thaliana. It upregulates the signalling peptide CLV3, which in turn inhibits WUS as a negative feedback loop to constrain SAM size.

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 Research Interests 

I’m generally interested in the application of formal methods (computer science, computational) on complex multi-scale (biological) systems and especially in systems where there are emergent phenomena. 

Biography